Primary Health Care (PHC) study
The Primary Health Care (PHC) study uses a pragmatic nested factorial design including a cluster randomised element to evaluate the implementation, effectiveness and cost effectiveness of different models of alcohol screening and brief intervention piloted in 24 typical primary health care practices in three English regions. The study will test three models of implementation: a control group receiving a patient information leaflet (PIL), brief advice(BA) provided by PHC staff plus PIL, and brief lifestyle counselling(BLC) provided by PHC staff plus BA and PIL. Two screening approaches (targeted vs universal) and two screening tools of different complexity will be compared (FAST and M-SASQ). 744 hazardous or harmful drinking patients will be recruited for the study (31 per PHC). PHC study outcomes will include measures of implementation, attitudinal and organisational predictors of implementation, and patient outcomes, which will include drinking behaviour, alcohol related problems, quality of life and health economic outcomes. The PHC study is designed to answer key policy questions concerning the implementation of screening and brief intervention in PHC (ISRCTN06145674).